Sanfilippo Syndrome-MPS-III

by Chavonne Jones

Sanfilippo syndrome, or Mucopolysaccharidosis III (MPS-III) is a rare genetic disorder caused by a deficiency in one of the enzymes needed to breakdown glycosaminoglycan heparan sulfate in the metabolism. The heparan sulfate slowly builds in the brain; causing hyperactivity, sleep disorders, loss of speech, and dementia.